Introduction About GLYCOMET-GP 2MG TABLET

What is Glycomet GP 2mg Tablet?

Glycomet-GP 2 Tablet is used to manage type 2 diabetes mellitus when diet, exercise and the single agent does not result in adequate glycemic control. It is a combination of Glimepiride and Metformin which belongs to a group of medicines called Antidiabetic agents. Glimepiride lowers blood sugar by causing the pancreas to produce more insulin and helps the body to use insulin efficiently. Metformin reduces the total amount of sugar released into the blood by the liver.

Take this medicine with meals to avoid stomach upset. Try not to skip doses and take the medicine at the same time each day for consistent control on blood sugar levels. If you are taking this medicine for chronic period, do not stop taking it abruptly without consulting your doctor. If you wish to reduce or increase the dose of Glycomet-GP, talk to your doctor for advice.

Combining Glycomet-GP with regular physician exercise and a healthy low-carb diet may help you effectively manage the signs of diabetes.

Before taking Glycomet-GP 2, inform your doctor if you have type 1 diabetes mellitus, diabetic ketoacidosis, severe liver or kidney disease, acute heart problems. Inform your doctor if you are pregnant or breastfeeding.

Avoid consumption of alcohol while taking Glycomet-GP 2 as it may increase the risk of lactic acidosis. The most common side effects of taking Glycomet GP 2 Tablet are taste disturbance, diarrhea or stomachache. Contact your doctor if any of the symptoms worsen.

Key Composition

• Glimepiride and Metformin 

Uses Of GLYCOMET-GP 2MG TABLET

• Management of type 2 diabetes mellitus (when diet, exercise and the single agent does not result in adequate glycemic control)

Benefits of Glycomet-GP for Diabetes Management

1. Effective Blood Sugar Control: Glycomet-GP helps reduce both fasting and post-meal blood sugar levels, making it effective in achieving optimal glycemic control.
2. Dual Mechanism of Action: Metformin enhances insulin sensitivity and reduces glucose production in the liver, while glimepiride stimulates the pancreas to produce more insulin.
3. Prevention of Complications: By maintaining stable blood sugar levels, Glycomet-GP helps lower the risk of diabetes-related complications such as neuropathy, retinopathy, and cardiovascular issues.
4. Weight-Neutral Effect: Unlike other medications, Glycomet-GP is less likely to cause significant weight gain, making it a preferred choice for individuals aiming to maintain a healthy weight.
5. Once-Daily Dosing: Glycomet-GP offers the convenience of a single daily dose, ensuring better compliance and ease of use for patients.

Why Choose Glycomet-GP for Diabetes Management?

Glycomet-GP is ideal for patients who struggle with high blood sugar levels despite lifestyle modifications. It’s effective, safe, and trusted by healthcare professionals worldwide.

How GLYCOMET-GP 2MG TABLET Works

Glycomet-GP 2 Tablet controls blood glucose levels, where Glimepiride works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin works by lowering glucose production in the liver, delaying glucose absorption from intestine, and increasing the body’s sensitivity to insulin.

How to use GLYCOMET-GP 2MG TABLET

Glycomet GP 2 Tablet is a prescription diabetes medication which should be used exactly as suggested by your doctor. Therefore, always consult your doctor before purchasing this medicine.

How to Take Glycomet GP 2 Tablet?

• Take Glycomet-GP 2 Tablet with meals, once or twice daily as told by your doctor.
• Swallow the medicine with a glass of water. Do not crush or chew the medicine.
• Try to take this medicine at the same time each day for consistency and ease of remembrance.

Glycomet-GP 2 – Recommended Dosage:

Typically prescribed once or twice daily, depending on the patient’s blood sugar levels and medical condition. The maximum recommended daily dose of Glimepiride (a component of Glycomet GP) is typically 8 mg, and Metformin is up to 2000-2550 mg/day, but this depends on individual patient factors.

What To Do If I Miss a Dose of Glycomet-GP 2:

• Avoid skipping doses, and if a dose is missed, take it as soon as you remember unless it’s almost time for the next dose. Do not double up doses to make up for a missed one.

Side Effects Of GLYCOMET-GP 2MG TABLET

Like all medicines, glycomet-GP 2 may cause certain side effects in some individuals, although not everybody gets them

Common side effects of Glycomet-GP Tablet:

• taste disturbance
• diarrhea
• stomach pain
• loss of appetite

When To Consult your Doctor?

Stop taking Glycomet-GP 2 and contact your doctor immediately if you experience any of the following side effects:

• lactic acidosis
• inflammation of the liver which may result in jaundice (yellowing of skin or eyes)
• severe allergic reactions (such as skin rash, hives, and increased sensitivity to sun, inflammation of blood vessels which may develop into serious reactions with difficulty in breathing, fall in blood pressure and sometimes progressing to shock)
• severe low blood sugar levels

Can Glycomet-GP 2 cause hypoglycemia?

Yes, Glycomet GP2 can cause hypoglycemia (low blood sugar) due to the Glimepiride component, which increases insulin secretion. This risk is higher if meals are skipped, with excessive exercise, alcohol use, or when combined with other antidiabetic medications. Always take it with food and monitor blood sugar regularly.

How To Manage Side Effects

Warning & Precautions

Diet and Lifestyle Advice

1. Dietary Modifications

• A diet rich in whole grains, vegetables, lean proteins, and healthy fats helps maintain stable blood sugar levels.
• Focus on low glycemic index (GI) foods, which release sugar into the bloodstream slowly (e.g., oats, legumes, sweet potatoes). Avoid foods with a high GI (e.g., white bread, sugary snacks).
• Eat smaller, frequent meals to maintain consistent blood sugar levels. Skipping meals can cause blood sugar fluctuations and increase the risk of hypoglycemia, particularly when using Glimepiride.
• Incorporating high-fiber foods (such as vegetables, fruits, legumes, and whole grains) helps regulate blood sugar and improve overall digestion?

• Avoid sugary sodas and juices as they can cause sudden spikes in blood glucose levels.

2. Regular Exercise

• Exercise is crucial for diabetes management. It helps the body use insulin more effectively, lowers blood sugar levels, and enhances cardiovascular health.

• Activities like walking, jogging, swimming, or cycling can improve heart health and help reduce insulin resistance.Aim for at least 30 minutes of moderate aerobic exercise (5 days a week).
• Incorporating weight lifting or resistance exercises (e.g., bodyweight exercises like squats or push-ups) helps increase muscle mass, which in turn improves the body’s ability to manage blood sugar. Perform strength training exercises 2-3 times per week?
• Yoga and stretching can enhance flexibility and reduce stress, both important for managing blood sugar levels.

3. Stress Management

• Chronic Stress can increase blood sugar levels due to elevated cortisol levels, which affect insulin efficiency.
• Mindfulness Meditation Can reduce stress and improve overall well-being.
• Slow, deep breathing can activate the parasympathetic nervous system and help manage stress
• Getting enough restful sleep (7-9 hours per night) is essential for managing diabetes. Sleep disturbances can lead to insulin resistance and negatively affect glucose metabolism.
• Create a sleep routine by going to bed at the same time each night and avoiding electronics or caffeine before bed.

5. Avoid SLimit Alcohol

• Smoking can increase the risk of diabetes complications, including heart disease and nerve damage. If you smoke, seek resources to help quit.
• Alcohol can interfere with blood sugar control, especially if taken in excess. It’s important to drink in moderation and monitor blood sugar levels when consuming alcohol .

6. Regular Monitorinal Follow-up

• Keep track of blood glucose levels regularly to understand how your lifestyle and medications (like Glycomet GP) are affecting your health.
• Visit a healthcare provider regularly to adjust medications, review progress, and manage any complications .

Related Health Articles:

Diabetic Diet Chart (1600 Calories, Vegetarian)

Diabetes: 5 Incredible Herbs For Controlling Blood Sugar Levels- Infographic

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Drug – Drug interaction

Drugs to avoid with Glycomet GP2:

1. Drugs That Increase the Risk of Hypoglycemia

• Other Antidiabetic Drugs: Combining Glimepiride with insulin, other sulfonylureas, or GLP-1 receptor agonists
•  can increase the risk of low blood sugar.
• Beta-Blockers (e.g., propranolol, metoprolol): Can mask symptoms of hypoglycemia, such as a rapid heartbeat.
• ACE Inhibitors (e.g., enalapril, lisinopril): May enhance the glucose-lowering effect of Glimepiride.

2. Drugs That Reduce Glycomet GP Efficacy

• Corticosteroids (e.g., prednisone): Can cause hyperglycemia, reducing the effectiveness of Glycomet GP.
• Thiazide Diuretics (e.g., hydrochlorothiazide): May raise blood sugar levels, counteracting the effects of Metformin.
• Thyroid Hormones (e.g., levothyroxine): Can interfere with glucose control.

3. Drugs That Increase the Risk of Lactic Acidosis with Metformin

• Alcohol: Can exacerbate the risk of lactic acidosis, a rare but serious side effect of Metformin.
• Iodinated Contrast Agents: Used in imaging procedures, these can increase the risk of kidney damage, leading to lactic acidosis when used with Metformin.
• NSAIDs (e.g., ibuprofen): May reduce kidney function and increase the risk of lactic acidosis when combined with Metformin.

4. Drugs That May Interact with Glimepiride’s Mechanism

• Enzyme-Inducing Drugs (e.g., rifampin, phenytoin): These can accelerate the metabolism of Glimepiride, reducing its effectiveness.
• Enzyme-Inhibiting Drugs (e.g., fluconazole): Can increase the concentration of Glimepiride, heightening the risk of hypoglycemia.

5. Anticoagulants and Glimepiride

• Warfarin: Glimepiride can alter the effect of warfarin, necessitating close monitoring of INR (International Normalized Ratio).

6. Interaction with Herbal Supplements

• Ginseng: May enhance the glucose-lowering effect of Glycomet GP, increasing the risk of hypoglycemia.
• St. John’s Wort: Can reduce the effectiveness of Glimepiride due to enzyme induction.

Synopsis

More Information

Both Glycomet-GP 2mg and Janumet are used for managing type 2 diabetes but differ in their composition. Glycomet-GP contains glimepiride, which increases insulin production, while Janumet contains sitagliptin, a DPP-4 inhibitor that enhances insulin secretion and suppresses glucagon release. Each option has its own benefits and side effects, so the choice depends on individual needs and medical advice.Bottom of Form

Alternatives to Glycomet GP:

Glycomet GP 2/850mg Tablet 10’S

Glycomet GP 0.5mg Tablet 10’S

Glycomet GP 1mg Tablet 15’S

Glycomet GP 3/850mg Tablet 10’S

FAQs About GLYCOMET-GP 2MG TABLET